Summary: A new study presented at the 2024 Annual Meeting of The Menopause Society suggests that hot flashes are more likely to occur during a the second part of the night when REM sleep predominates, potentially increasing the risk of cardiovascular disease in perimenopausal … [Read more...]
Incannex Secures Up to $60M to Support Clinical Trials
Summary: Incannex Healthcare Inc announced it has entered into a financing agreement with Arena Investors LP, securing up to $10 million in convertible notes and a $50 million equity line of credit. The funds will be used to advance clinical trials for its lead product, IHL-42X, … [Read more...]
Can Wearable Sleep Devices Flag Early Signs of Alzheimer’s Disease?
Summary: The National Institutes of Health awarded $3.9 million to Joyita Dutta, PhD, at UMass Amherst to investigate whether wearable sleep trackers can detect early signs of Alzheimer’s disease by correlating sleep patterns with blood biomarkers. The study will monitor sleep … [Read more...]
No-Sleep Challenge: The Dangers of Sleep Deprivation
By Adam Taylor, Lancaster University Most of us will be all too familiar with that dopey, groggy feeling of being tired after a restless night. Some social media users have taken tiredness to the extreme, however, by taking part in what they call a “no-sleep challenge.” One … [Read more...]
Epilepsy Drug Slashes Breathing Pauses in OSA Patients
Summary: A clinical trial presented at the European Respiratory Society Congress in Vienna revealed that the epilepsy drug sulthiame significantly reduced symptoms of obstructive sleep apnea (OSA) in patients who cannot tolerate CPAP therapy. The study, conducted across multiple … [Read more...]
ORX750 Significantly Increased Wakefulness in Sleep-Deprived Individuals
Summary: Centessa Pharmaceuticals announced positive interim data from its ongoing phase 1 trial of ORX750, an orexin receptor 2 agonist, in acutely sleep-deprived healthy volunteers. The trial demonstrated that ORX750 significantly increased wakefulness, with the 2.5 mg dose … [Read more...]
Tomato-Derived Melatonin Ingredient Achieves Self-Affirmed GRAS Status
Summary: A tomato-derived melatonin ingredient, Somato, has achieved self-affirmed Generally Recognized As Safe (GRAS) status in the US. This plant-based alternative to synthetic melatonin is extracted using a proprietary process and has gained traction internationally, … [Read more...]
Playing with Fabric – Bouquet
Playing with fabric is addictive. Playing with fabric for one of my favorite patterns is a blast! I thought I’d see what Bouquet would look like in some different fabric combinations.I’ve made Bouquet several times. It’s a good pattern for making in what I like to call … [Read more...]
Apple Watch Gets Sleep Apnea Detection Feature
Summary: Apple’s new update for the Apple Watch includes a feature to help detect signs of sleep apnea by using the device’s accelerometer to track breathing disturbances during sleep. This feature provides users with notifications when patterns suggest possible sleep apnea, … [Read more...]
Heavy Cannabis Use Actually Hurts Sleep—and Memory: Study
Summary: A recent study led by researchers from The University of Texas at Dallas and the University of Amsterdam has revealed that long-term cannabis use negatively impacts both sleep and memory. The study, which included 141 adults with cannabis use disorder and 87 non-users, … [Read more...]
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